Metabolic Wellness Profile: Summary
In this Lab&Learn, Dr. Aron Gonshor joins to discuss metabolic wellness through the lens of the Metabolic Wellness Profile, a test done using dried urine samples. The discussion covers three main aspects: protein metabolism, liver detoxification, and oxidative stress.
Dr. Gonshor provides an in-depth look at protein digestion, particularly focusing on the implications of indican levels which signal issues like dysbiosis and protein malabsorption, and various solutions including enzyme supplementation and dietary adjustments. The podcast also delves into liver detoxification, emphasizing the liver’s numerous functions and the problems arising from dysfunction, such as oxidative stress and chronic illnesses. Key points include the importance of bile acids and their role in detoxification, and the impacts of external and internal toxins on liver health.
Finally, oxidative stress is explained as a contributor to cellular damage and chronic conditions, with an emphasis on the significance of the 8-OHdG biomarker for evaluating cumulative cellular oxidative stress, and how lifestyle and dietary adjustments can help mitigate these effects.
The episode concludes with a Q&A session addressing various related topics, including the significance of detecting these biomarkers and potential next steps for affected individuals.
Metabolic Wellness Profile: Topics
00:00 Introduction to Dr. Aron Gonshor
00:29 Overview of Metabolic Wellness Profile
03:54 Understanding Protein Metabolism
09:16 Liver Detoxification Explained
23:59 Oxidative Stress and Its Impact
27:48 Understanding Chronic Inflammation and Oxidative Stress
28:58 Key Biomarker: 8-OHdG
30:07 Sources and Effects of Oxidative Stress
33:41 Healthy Lifestyle Choices and Antioxidant Supplements
34:58 Melatonin: More Than Just Sleep
36:44 Reading and Interpreting Lab Reports
37:45 Addressing High Indican Levels
39:40 Elevated 8-OHdG and Its Implications
42:36 Low Bile Acids: Causes and Action Plan
44:15 Q&A Session
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